It is recommended that caffeine be discontinued for at least 24 hours prior to stress testing. Theophylline is related chemically to the natural metabolite xanthine, which is a precursor of uric acid. Methylxanthines are bronchodilators used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Learn vocabulary, terms, and more with flashcards, games, and other study tools. The immediate nursing care of patients with asthma depends on the severity of symptoms. Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). Describe the side effects of beta 2-adrenergic agonists and methylxanthines. Please consult the latest official manual style if you have any questions regarding the format accuracy. Therefore, a calm approach is an important aspect of care. Citation. Methylxanthines -inhibits phosphodiesterase leads to incr. Specific xanthine agents. Monitor therapeutic effectiveness which is indicated by relief from pain and cramping in calf muscles, buttocks, thighs, and feet during exercise and improves walking performance (time and duration). METHYLXANTHINES EXPECTED OUTCOMES? Narrow margin of safety & high risk of toxicity - SX: anorexia, N/V, restlessness, insomnia, seizures, dysrhythmias. Less frequent nocturnal asthma. Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. METHYLXANTHINES PATIENT TEACHING? Liver disease. Find patient medical information for Duoneb Inhalation on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Reginald P. Sequeira, in Side Effects of Drugs Annual, 2009. Assessment & Drug Effects. • Phenobarbital and phenytoin decrease theophylline levels. Start studying MCC nursing 1355. Methylxanthines; Nursing Management. Describe the therapeutic serum or plasma theophylline level and the toxic level. The patient and family are often frightened and anxious because of the patient’s dyspnea. IV Therapeutic Level: 10 - 20. Caffeine: (Major) Methylxanthines, through antagonism of adenosine and thus pharmacologic-induced coronary vasodilation, have been associated with false-negative results during dipyridamole-thallium 201 stress testing. histamine release -stimulates ciliary transport of ... Drug Mechanism Use Side/Adverse Effects Nursing Implications Cromolyn Sodium (non-steroidal) INTAL -prevents influx of Ca into mast cells, therefore inhibiting degranulation and release of Because of their methyl attachments, these agents are often referred to as methylxanthines. cAMP so bronchodilation -decr. Nursing Implications. Methylxanthines (nursing considerations: • Advise clients to avoid consuming caffeinated beverages (coffee, caffeinated colas). Monitor BP if patient is also on antihypertensive treatment. Contrast the therapeutic effects of leukotriene antagonists, glucocorticoids, cromolyn, antihistamines, and mucolytics for COPD and asthma. Although nursing considerations and implications are slightly different, most nursing resources and textbooks use them interchangeably. METHYLXANTHINES NURSING IMPLICATIONS?